Biochemistry is closely related to molecular biology, the study of the molecular mechanisms by which genetic information encoded in DNA is able to result in the processes of life. Depending on the exact definition of the terms used, molecular biology can be thought of as a branch of biochemistry, or biochemistry as a tool with which to investigate and study molecular biology. The present and the future role of biochemistry in the search for a new therapeutic agent is reviewed. It is stated that the great importance of the various disciplines of biochemistry, including patho-biochemistry and pharmacological biochemistry, is presently recognized, and the involvement of biochemistry in drug research is increasing. Biochemistry at the present time and in the future will utilize the already known basic biological principles for the new development of new and more useful medicines. It is emphasized that the limiting factor in new drug discovery today, however, is the lack of new basic discoveries in biology.