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Radboud University, Netherlands
Title: Cationic gemini and geminoid peptide amphiphiles: From transfection to protease inhibition

Graduated in biochemistry, bio-organic chemistry and food chemistry; PhD on structure-function relationship of the enzyme; postdoctoral work in X-ray absorption spectroscopy. Bachelor and master teaching on the subjects of organic chemistry, (bio)-inorganic chemistry, instrumental analysis, advanced spectroscopy, and advanced molecular structure determination; master and advanced courses on biocatalysis, homogeneous catalysis, X-ray absorption spectroscopy, and chemistry of metals in biological systems.


Gemini surfactants are amphiphilic molecules containing two head groups and two aliphatic tails which are linked by a spacer between the head groups, or between the linker region connecting the heads and the tails.1 Because their critical aggregate concentration is 103-fold lower they are more effective surfactants than the corresponding monovalent compounds (i.e. classical surfactants with a single chain and a single head group), which makes them interesting for various biomedical applications. Cationic geminis have shown to be viable agents for transfection, the introduction of nucleotides into a eukaryotic cell, thereby providing an alternative to viruses and cationic polymers.2 Amphiphilic peptides consisting of a peptide spacer with the N- and C-termini appended with hydrophobic groups are asymmetric geminis and are called gemini-like or geminoids. Interestingly, the SPKR geminoid with unsaturated alkyl tails can achieve transfection without the lysogenic helper lipid that is required in other cases.3 The proteases involved in the maturation of the polyprotein of dengue virus to new virus particles have cationic peptide sequences as their preferred substrates. Saturated geminoids of the KGnK and KAnK series (n = 1 or 2) are inhibitors of dengue virus 2 protease and the host protease furin, with slight selectivity of one over the other.4,5 The inhibitors are also active against dengue virus 2 infection in a cellular context, at concentrations below which they are toxic

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Delegates are personally responsible for their belongings at the venue. The Organizers will not be held responsible for any stolen or missing items belonging to Delegates, Speakers or Attendees; due to any reason whatsoever.


Registration fees do not include insurance of any kind.


Please note that any (or) all transportation and parking is the responsibility of the registrant.


Press permission must be obtained from Allied Academies Organizing Committee prior to the event. The press will not quote speakers or delegates unless they have obtained their approval in writing. The Allied academies are a non-profit organization. This conference is not associated with any commercial meeting company.

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For security purposes, letter of invitation will be sent only to those individuals who had registered for the conference. Once your registration is complete, please contact us to request a personalized letter of invitation.

Regarding refunds, all bank charges will be for the registrant's account.

Cancellation, Postponement and Transfer of Registration

All cancellations or modifications of registration must be made in writing to Program Manager(

Cancellation Policy

If Allied academies cancel this event for any reason, you will receive a credit for 100% of the registration fee paid. You may use this credit for another Allied Academies Conferences (AAC) event which must occur within one year from the date of cancellation.


If Allied academies postpone an event for any reason and you are unable or unwilling to attend on rescheduled dates, you will receive a credit for 100% of the registration fee paid. You may use this credit for another Allied Academies Conferences event which must occur within one year from the date of postponement.

Transfer of registration

All fully paid registrations are transferable to other persons from the same organization if registered person is unable to attend the event. Transfers must be made by the registered person in writing to Program ManagerDetails must be included with the full name of replacement person, their title, contact phone number and email address. All other registration details will be assigned to the new person unless otherwise specified.

Registration can be transferred to one conference to another conference of Allied academies if the person is unable to attend one of conferences.

However, Registration cannot be transferred if it is intimated within 14 days of the respective conference.

The transferred registrations will not be eligible for Refund.

Visa Information

Keeping in view of increased security measures, we would like to request all the participants to apply for Visa as soon as possible.

Allied Academies will not directly contact embassies and consulates on behalf of visa applicants. All delegates or invitees should apply for Business Visa only.

Important note for failed visa applications: Visa issues cannot come under the consideration of cancellation policy of Allied Academies, including the inability to obtain a visa.

Refund Policy:

If the registrant is unable to attend, and is not in a position to transfer his/her participation to another person or event, then the following refund arrangements apply:

Keeping in view of advance payments towards Venue, Printing, Shipping, Hotels and other overheads, we had to keep Refund Policy is as following slabs-

  • Before 60 days of the conference: Eligible for Full Refund less $100 service Fee
  • Within 60-30 days of Conference: Eligible for 50% of payment Refund
  • Within 30 days of Conference: Not eligible for Refund
  • E-Poster Payments will not be refunded.

Accommodation Cancellation Policy:

Accommodation Providers (Hotels) have their own cancellation policies, and they generally apply when cancellations are made less than 30 days prior to arrival. Please contact us as soon as possible, if you wish to cancel or amend your accommodation. Allied Academies will advise the cancellation policy of your accommodation provider, prior to cancelling or amending your booking, to ensure you are fully aware of any non-refundable deposits

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