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György Keglevich graduated from the Technical University of Budapest in 1981 as a chemical engineer. He got “Doctor of Chemical Science” degree in 1994, in the subject of organophosphorus-chemistry. He has been the Head of the Department of Organic Chemistry and Technology since 1999. Within organophosphorus chemistry, his major field embraces a P-heterocycles involving selective syntheses, as well as bioactive and industrial aspects. He also deals with environmentally friendly chemistry involving MW chemistry, its theoretical aspects, phase transfer catalysis, the development of new chiral catalysts, and the use of ionic liquids. He is the author or co-author of ca. 550 papers (the majority of which appeared in international journals) including ca. 70 review articles and 40 book chapters. He is, among others, the member of the Editorial Board of Molecules, Heteroatom Chemistry and Phosphorus, Sulfur and Silicon, and the Related Elements, and Current Microwave Chemistry. He is the Editor-in-Chief for Current Organic Chemistry and Current Green Chemistry, the co-Editor-in-Chief for Current Catalysis, Associate Editor for Current Organic Synthesis and Letters in Drug Design and Discovery, and Regional Editor for Letters in Organic Chemistry.
Co-authors: Réka Henyecz, Nóra Zs. Kiss, Zita Rádai, Anna Tripolszky, Nikoletta Harsági, Petra R. Varga, Alajos Grün The microwave (MW) technique has become an important tool in organophosphorus chemistry. In this paper, the advantages of MWs in different catalytic reactions are surveyed allowing green chemical accomplishments. The first case is, when the MW-assisted direct esterification of phosphinic acids and phosphonic acids becomes more efficient in the presence of an ionic liquid catalyst. The second instance is, when catalytic reactions, such as the phase transfer catalyzed (PTC) O-alkylation of phosphonic acids are promoted further by MW irradiation. It is also an option that MWs may substitute catalysts, such as in the Kabachnik–Fields condensations of amines, aldehydes and >P(O)H reagents. Another valuable finding of ours is that in the Hirao P–C coupling of 3P(O)H reagents and bromoarenes applying Pd(OAc)2 as the catalyst, the slight excess of the >P(O)H species in its tautomeric >POH form may substitute the usual P-ligands. Pd- and Ni-catalyzed cases exploring the mechanisms will be shown. The Pudovik reaction and the synthesis of dronic acid derivtives as medicines will also be discussed. It is also the purpose of this paper to elucidate the scope and limitations of the MW tool. Supports from National Research Development and Innovation Office in the frame of FIEK_16-1-2016-0007 and BME FIKP-BIO by the Ministry of Human Capacities of Hungary are acknowledged.