Medicinal compounds are organic in nature and are classified into small organic molecules and biologics. In many cases Inorganic and organometallic compounds are also useful as drugs. The most common practice of medicinal chemistry, is aiming to discover and develop new therapeutic agents by involving synthetic organic chemistry and computational chemistry in a close knit combination with chemical biology, enzymology and structural biology.The interdisciplinary team-work at the interface between chemistry, biology and medicine is required for Drug research. The discipline of Medicinal chemistry is both science and an art. The former offers humankind its best hopes for improving the living quality and the latter, still challenges its researchers with the need for both intuition and experience to discover new drugs.